Structured, AI-Assisted Method Development for Analytical Chemistry
Design Better Methods. With Structure.
The LabVeda Method Engine transforms method development from trial-and-error into systematic scientific strategy. Built specifically for analytical chemists, it combines AI-assisted workflows with real-world chromatography expertise to help you design, optimize, and refine HPLC and LC–MS methods with clarity and confidence.
Why Traditional Method Development Is Inefficient
Method development often relies on:
- Iterative gradient guesswork
- Informal parameter adjustments
- Fragmented documentation
- Experience locked in individuals
This approach slows progress and reduces reproducibility.
The Method Engine replaces guesswork with structured logic.
What the Method Engine Delivers
🔬 Gradient Design Guidance
Structured selection of starting %B, slope, and runtime strategy based on analyte behavior.
⚗ Mobile Phase Optimization
Systematic evaluation of pH, buffer strength, additive choice, and solvent composition.
📈 Selectivity & Resolution Strategy
Logic-based column chemistry and parameter refinement recommendations.
📊 Robustness Evaluation Framework
Identify sensitivity to injection volume, temperature, buffer concentration, and system variability.
📘 Regulatory-Aware Structure
Supports defensible decision-making for GLP, GCP, and QC environments.
Designed For
- HPLC and UHPLC method development
- LC–MS method optimization
- Small molecule analytical workflows
- Bioanalysis laboratories
- QC and regulated environments
Whether building a method from scratch or optimizing an existing assay, the Method Engine provides a structured path forward.
How It Works
1️⃣ You define your analytical goal and constraints
2️⃣ The engine maps key variables to structured development logic
3️⃣ AI-assisted scoring highlights optimal parameter strategies
4️⃣ You receive clear, actionable development guidance
The output includes:
- Recommended parameter ranges
- Structured testing sequence
- Mechanistic rationale
- Robustness checkpoints
This is not automated guesswork — it is structured analytical intelligence.
Built on Applied Expertise
The Method Engine is grounded in:
- 15+ years of chromatography and LC–MS experience
- Practical laboratory workflows
- Regulatory-aware development strategies
- A hybrid human + AI model that maintains scientific rigor
LabVeda transforms tacit laboratory expertise into scalable decision systems.
Part of the LabVeda Scientific Intelligence Platform
The Method Engine integrates with:
- Chromatography Troubleshooting Decision Engine
- LC–MS Peak Integrity diagnostics
- Community-driven knowledge exchange
Together, they form an evolving AI Scientific Intelligence Platform for analytical chemistry.