Scientific Intelligence for Analytical Laboratories
Diagnose chromatography problems in minutes, not days. Structured decision engines built by chromatographers with 15+ years at the bench — every recommendation grounded in documented chromatographic evidence. Free to use, no signup required.
Diagnostic engines, built from bench experience
Each tool walks you through a structured diagnostic interview and returns ranked root-cause hypotheses with corrective actions. Open, free, and public.
Chromatography Troubleshooting Decision Engine
Any HPLC symptom, one starting point. Describe what you’re seeing and the engine narrows hundreds of failure modes to the few that fit your evidence.
Run the engineHigh Backpressure Troubleshooter
Column pressure climbing or spiking? Isolate the blockage — frit, guard, tubing, or column bed — in under ten questions.
Diagnose backpressurePeak Tailing Troubleshooter
Tailing factor out of spec? Distinguish silanol effects, column overload, extra-column volume, and injection-solvent mismatch systematically.
Fix peak tailingLC-MS PK Peak Integrity Engine
Purpose-built for pharmacokinetic assays: interrogate carryover, matrix effects, ion suppression, and integration integrity before your data goes to QC.
Check peak integrityHow the AI diagnosis works
Not a chatbot guessing — a structured decision engine encoding real chromatographic reasoning.
Describe your symptom
Start from what the chromatogram shows: tailing, drift, ghost peaks, pressure, carryover, lost sensitivity.
Answer guided questions
The engine asks the same discriminating questions an expert would — when it started, what changed, what a blank shows.
Get ranked root causes
Receive hypotheses ordered by likelihood, each with concrete corrective actions and verification checks.
Start from your symptom
Jump straight to the guide or tool for the problem on your screen right now.
Latest from the Knowledge Hub
Practical troubleshooting guides written for working analytical chemists — each linked to the tool that solves it.

Autosampler Carryover in HPLC and LC-MS: How to Find It and Wash It Out
Carryover is one of the quietest ways an autosampler can wreck your data. A trace of analyte left behind from a previous…

HPLC Baseline Noise and Drift: How to Tell Them Apart and Fix Each
An unstable baseline is one of the most common — and most time-consuming — problems in HPLC; by some estimates, baseline issues…

Ghost Peaks in HPLC: What Causes Them and How to Eliminate Them
You inject a blank — pure solvent, no sample — and peaks appear anyway. Or your gradient runs show extra peaks that…
Free membership, built for your workflow
Every tool works without an account. Join free when you want your work to persist.
Scientists helping scientists
LabVeda is a San Francisco–based Scientific Intelligence platform for analytical laboratories, founded by scientists who’ve spent years at the bench with HPLC, UHPLC, and LC-MS. That hands-on expertise powers three things: diagnostic intelligence for troubleshooting and method development, a scientific knowledge engine of evidence-grounded guides, and a community built on a simple idea: scientists helping scientists.
